Antibody Effectively Suppresses HIV Infection During First Human Trial

150408133040-largeAn antibody designed to fight HIV that generated excitement last year when it was proven to work well in monkeys has now been shown effective in humans.

The results of a phase 1 clinical trial using antibody 3BNC117 were published a few days ago in the journal, Nature.

In the trial, researchers injected the antibody into 29 volunteers, 17 with HIV and 12 without. The subjects received one intravenous dose of 1, 3, 10, or 30 milligrams of the antibody.

“Among HIV-infected participants, 3BNC117 had the greatest effect on the eight participants who received the highest dose, resulting in significant and rapid decreases in viral load,” the National Institutes of Health (NIH) reported in a news release. “HIV resistance to 3BNC117 was variable, but some individuals remained sensitive … for 28 days.” Continue reading

Meet The First Man Cured Of HIV

The "Berlin Patient" Timothy Ray Brown Holds News Conference On AIDS Cure TreatmentTimothy Ray Brown is the first and only person in the world to be cured of HIV. There are some fascinating parts to his story you may not know, but first, here’s a little background.

In 2007, Timothy was a gravely ill leukemia patient living in Berlin (after his cure he was famously known as “the Berlin patient” before he came forward in 2011 and identified himself). Timothy was also HIV-positive, but at the time, his HIV was the least of his worries.

When Timothy needed a stem cell transplant to treat his leukemia, doctors located a donor who had a rare gene mutation known as CCR5, which makes human cells immune to HIV. The result of the stem cell transplant? Timothy’s immune system was replaced with a brand new immune system minus the HIV, and to this day he remains the only person to be cured.

“The HIV is gone and it is gone for good,” says Timothy, who today lives in Palm Springs. “And I am also cancer free. Two cures. I am really fortunate and blessed.”

His cure is now part of the scientific record, but there are more interesting tidbits to learn about this courageous gay man who risked it all and found himself making history in the process.

Here are five things about Timothy Ray Brown that you may not know: Continue reading